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【包邮】BI–2852
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产品编号 GC35513
BI–2852 is a potent inhibitor of KRAS that binds with nanomolar affinity to a pocket between switch I and II on RAS· BI–2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells·
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