|
【包邮】Remibrutinib
收藏
产品编号 GC38375
Remibrutinib (LOU064) is a potent, highly selective covalent inhibitor of bruton tyrosine kinase (BTK) with IC50 of 1·3 nM, 2·5 nM and 18 nM for BTK, FcγR–induced IL8 and anti–IgM/IL4–induced CD69, respectively· Remibrutinib (LOU064) exhibits an exquisite kinase selectivity due to binding to an inactive conformation of BTK and has the potential for the treatment of autoimmune diseases·
|