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【包邮】Ixazomib?citrate
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产品编号 GC36356
Ixazomib citrate (MLN9708, Ninlaro) is a prodrug of Ixazomib (MLN2238), which is a selective, orally bioavailable inhibitor of 20S proteasome that inhibits the chymotrypsin–like proteolytic (β5) site with IC50 of 3·4 nM and Ki of 0·93 nM, respectively· Ixazomib (MLN2238) also inhibits caspase–like (β1) and trypsin–like (β2) proteolytic sites with IC50 of 31 nM and 3500 nM, respectively·
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