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【包邮】MPT0B098
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产品编号 GB40282
Microtubule inhibitor that binds to the colchicine–binding site of tubulin and suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability· MPT0B098 arrests cells in the G2–M phase and subsequently induces cell apoptosis· In addition, MPT0B098 effectively suppresses VEGF–induced cell migration and capillary–like tube formation of HUVECs· MPT0B098 not only inhibited the expression levels of HIF–1α protein but also destabilized HIF–1α mRNA·
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